2019 Neuroscience Symposium

Brain Oscillations in Parkinson’s Disease

     The motor symptoms of Parkinson's disease result from abnormal patterns of activity in surviving nondopaminergic neurons of the the basal ganglia following loss of dopaminergic cells in the substantia nigra. The most prominent component of abnormal activity is an exaggerated oscillation in the beta frequency range (10-30 Hz) in field potentials and neuronal firing patterns in humans with the disease and in animal models of parkinsonism.  

     Following an introduction to Parkinson’s disease, deep brain stimulation and pathologic oscillations by Dr. Jerrold Vitek, our panel will present a series of lectures that address 1) the causal role for exaggerated oscillations in Parkinson's disease; 2) experimental studies of the origin of normal and maladaptive basal ganglia oscillations; and 3) existing and potential treatments aimed at disrupting oscillatory activity associated with the disease symptoms.

How do oscillations engage brain networks?  

Entrainment & synchrony in the basal ganglia

Exploring the significance of exaggerated oscillatory

local field potential activity in the Parkinsonian rat

September 12, 2019 | 9a-5p

BSE 2.102 | UTSA Main Campus

Free & open to the public

Robert S. Turner PhD

Professor of Neurobiology

University of Pittsburgh

Oscillations & deep brain stimulation

Judith R. Walters PhD

Senior Investigator


Charles J. Wilson PhD

Ewing Halsell Distinguished Chair

University of Texas San Antonio


Bevan PhD



Turner PhD

U Pittsburgh

Maladaptive plasticity of the subthalamic nucleus

in mouse models of Parkinson’s disease

Mark Bevan PhD

Professor in Physiology

Northwestern University

Oscillatory activity in the basal ganglia:

Is it enough to explain Parkinson’s disease?

Jerrold L. Vitek MD PhD

Mcknight Professor & Chair

University of Minnesota

Symposium Introduction

Parkinson's disease, deep brain stimulation & pathologic oscillations

Jerrold L. Vitek MD PhD

Mcknight Professor & Chair of Neurology

University of Minnesota

Panel Lectures, in order of appearance